The ability to image protein-protein interactions (PPIs) in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine. The visual representation, characterization, quantification, and timing of these biological processes in living subjects can complement in vitro or cell culture methodologies.
Read this white paper to learn how bioluminescence resonance energy transfer (BRET) was used to monitor PPIs using non-invasive in vivo imaging.